Choosing the Right Python GUI Framework: A Complete Guide

Choosing the Right Python GUI Framework: A Complete Guide

When it comes to developing graphical user interfaces (GUIs) in Python, there are several frameworks available that can make your life as a developer much easier. Python GUI frameworks provide a set of tools and libraries that enable developers to create visually appealing and interactive applications with ease.

If you are looking to choose the best fit for your business or use-case, then you’ve come to the right place!  In this article, we will explore the best Python GUI frameworks and discuss their features, benefits, and use cases.

What is a Python GUI?

A Python GUI, or Graphical User Interface, is a visual interface that allows users to interact with a software application. It provides users with a set of graphical elements, such as buttons, checkboxes, dropdown lists, and sliders, to perform various tasks and access different functionalities of the application. Python GUI frameworks enable developers to create these interfaces efficiently by providing a set of tools, libraries, and pre-built components that simplify the development process.

Benefits of Using Python GUI Frameworks

Python GUI frameworks offer several advantages over building GUIs from scratch. Firstly, these frameworks provide a rich set of pre-built widgets and components that can be easily customized to suit your application's needs. This saves you a significant amount of time and effort in designing and implementing the basic building blocks of your GUI.

Secondly, Python GUI frameworks abstract away the low-level details of GUI programming, making it easier for developers to focus on the application logic rather than the intricacies of the graphical interface. This allows you to write clean and maintainable code, reducing the chances of errors and improving the overall quality of your application.

Lastly, Python GUI frameworks are highly extensible and support integration with other libraries and tools. Whether you need to connect your GUI application to a database or leverage the power of data visualization libraries, these frameworks provide seamless integration options, enabling you to create robust and feature-rich applications.

A GUI framework is also essential for effective GUI development in Python. It offers several advantages that make the life of a developer easier:

  • Consistency: GUI frameworks ensure consistency in design and functionality across different screens and devices, providing a seamless user experience.
  • Customizability: GUI frameworks offer a wide range of customization options, allowing developers to tailor the interface according to their specific requirements and branding.
  • Cross-platform Compatibility: Many GUI frameworks support cross-platform development, enabling developers to create applications that run on different operating systems without significant modifications.

Comparison of the Best Python GUI Frameworks

There are several Python GUI frameworks available, each with its own strengths and weaknesses. Let's take a look at the most popular ones and compare their features.


Tkinter is the standard GUI framework for Python. It is a wrapper around the Tk GUI toolkit, which was originally developed for the Tcl scripting language. Tkinter provides a set of easy-to-use classes and functions that allow developers to create simple and intuitive GUI applications.


  • One of the major advantages of Tkinter is its simplicity. It has a small learning curve, making it an ideal choice for beginners. 
  • Support for both commercial and open-source projects.
  • Tkinter is included with most Python distributions, which means you don't have to install any additional libraries to get started.


  • Tkinter's simplicity comes at the cost of limited customization options. While it provides a basic set of widgets like buttons, labels, and entry fields, creating complex and visually appealing GUIs can be challenging with Tkinter alone. 
  • The default look and feel may appear outdated compared to modern interfaces.


PyQT is a comprehensive set of Python bindings for the Qt application framework. Qt is a powerful and versatile GUI toolkit that provides a wide range of features and capabilities. PyQT combines the simplicity of Python with the power of Qt, making it an excellent choice for developing complex and visually stunning GUI applications.


  • One of the key advantages of PyQT is its extensive set of widgets and components.
  • Provides a vast collection of pre-built widgets that can be easily customized to create highly interactive and modern-looking GUIs. 
  • Supports advanced features like internationalization, network programming, and multimedia integration, making it suitable for a wide range of applications.


  • PyQT has a steeper learning curve compared to Tkinter due to the complexity of the Qt framework.


Kivy is an open-source Python framework for developing multi-touch applications. It is designed to be cross-platform, which means that you can write your GUI application once and deploy it on multiple platforms without any modifications. Kivy provides a rich set of tools and widgets that enable developers to create highly interactive and visually appealing applications.


  • Kivy supports touch input and gestures. It allows you to create touch-enabled applications that can run on devices like smartphones and tablets. 
  • Provides a powerful graphics engine that supports hardware acceleration, enabling you to create smooth and responsive user interfaces.
  • Open-source and free to use.


  • Kivy has a relatively small community compared to other Python GUI frameworks, which means that finding resources and support may be more challenging. 
  • Unique syntax and programming paradigm, which may require some time to get used to.


wxPython is a Python wrapper for the wxWidgets C++ library. wxWidgets is a mature and stable GUI toolkit that provides a native look and feel on multiple platforms, including Windows, macOS, and Linux. wxPython combines the power of wxWidgets with the simplicity of Python, making it a reliable choice for developing cross-platform GUI applications.


  • wxPython offers a native look and feel. It provides native widgets and controls that seamlessly integrate with the underlying operating system, giving your application a polished and professional appearance. 
  • wxPython also supports advanced features like drag-and-drop, printing, and clipboard operations, making it suitable for a wide range of applications.


  • wxPython has a smaller user base compared to Tkinter and PyQT, which means that finding resources and support may be more limited.
  • Steeper learning curve compared to Tkinter due to the complexity of the wxWidgets library.
  • Limited customization options compared to some other frameworks.


PySimpleGUI is a lightweight and easy-to-use Python GUI framework designed for beginners and developers looking for a quick and simple way to create graphical interfaces. It focuses on simplicity and ease of use, allowing developers to create basic GUI applications with minimal code.


  • Exceptional ease of learning and using the framework.
  • Cross-platform compatibility, allowing applications to run smoothly on various operating systems.


  • Limited customization options compared to more advanced frameworks.
  • Not suitable for complex and feature-rich applications.

Choosing the Right Python GUI Framework for Your Project

Choosing the right Python GUI framework for your project depends on several factors, including the complexity of your application, your familiarity with the framework, and the specific requirements of your project. Here are some guidelines to help you make an informed decision:

  1. Simplicity vs. Power: If you are new to GUI programming or developing a small to medium-sized application, Tkinter is a good choice due to its simplicity and widespread adoption. If you need advanced features and customization options, PyQT or wxPython may be more suitable.
  2. Cross-Platform Compatibility: If your application needs to run on multiple platforms without any modifications, Kivy or wxPython are good options due to their cross-platform capabilities.
  3. Touch Input and Gestures: If you are developing a touch-enabled application for mobile platforms, Kivy is the most suitable choice due to its extensive support for touch input and gestures.
  4. Native Look and Feel: If you want your application to have a native look and feel on multiple platforms, wxPython is the best choice due to its integration with the underlying operating system.

It is also worth considering the availability of resources, community support, and documentation for each framework. Take the time to explore the official documentation, online tutorials, and community forums to get a sense of the level of support available for each framework.

Best Practices for Developing with Python GUI Frameworks

Regardless of the Python GUI framework you choose, there are some best practices that you should follow to ensure a smooth and efficient development process:

  • Separation of Concerns: Separate your application logic from the GUI code by following the Model-View-Controller (MVC) or Model-View-ViewModel (MVVM) design patterns. This will make your code more modular, reusable, and easier to maintain.
  • Use Layout Managers: Take advantage of layout managers provided by the framework to easily position and resize your widgets. This will ensure that your GUI looks consistent across different screen sizes and resolutions.
  • Handle User Input Gracefully: Implement proper error handling and validation to handle user input effectively. Provide meaningful error messages and feedback to guide users and prevent crashes or unexpected behavior.
  • Optimize Performance: Use lazy loading and caching techniques to optimize the performance of your GUI application. Avoid unnecessary computations and ensure that your application responds quickly to user interactions.
  • Testing and Debugging: Test your application thoroughly to ensure that it works as expected. Use debugging tools and techniques provided by the framework to identify and fix any issues or bugs.

By following these best practices, you can ensure that your Python GUI application is well-structured, efficient, and user-friendly.


Python GUI frameworks provide a powerful set of tools and libraries that enable developers to create visually appealing and interactive applications with ease. Each framework has its own strengths and weaknesses, and the choice depends on various factors such as the complexity of your application, cross-platform compatibility, touch input requirements, and native look and feel.

Regardless of the framework you choose, it is important to follow best practices such as separation of concerns, using layout managers, handling user input gracefully, optimizing performance, and thorough testing and debugging. By following these guidelines, you can develop high-quality GUI applications that meet the needs of your users and provide a seamless user experience.

Additionally, as projects scale or demand for faster delivery increases, you might want to explore low-code solutions that can accelerate the development process. One such platform is ToolJet. ToolJet is a low-code platform specifically designed for building internal applications swiftly. Unlike traditional frameworks, ToolJet simplifies the connection to most databases, reducing the complexity involved in backend development. This feature is invaluable for projects that require real-time data interactions.

ToolJet is not just a low-code platform; it also embraces the power of Python and JavaScript. Developers have the option to write Python or JavaScript code whenever necessary, blending the ease of low-code development with the flexibility and power of Python. 

Next time you begin on a GUI development journey in Python, consider the best Python GUI frameworks discussed in this article, scaling options and make an informed choice based on your specific requirements.

Frequently asked questions

  1. Is Python suitable for GUI development?

Yes, Python is suitable for GUI development. It provides several libraries and frameworks that make it easy to create graphical user interfaces. Some popular options include Tkinter, PyQt, PySide, Kivy, and wxPython. These libraries offer a wide range of features and functionalities, allowing developers to create interactive and visually appealing GUI applications using Python.

  1. Can I create mobile applications using Python GUI frameworks?

 Yes, you can create mobile applications using Python GUI frameworks like Kivy. Kivy is specifically designed for developing multitouch applications and supports various platforms, including Android, iOS, Windows, macOS, and Linux. With Kivy, developers can build mobile apps with rich and interactive user interfaces using Python. It provides a wide range of UI components and supports touch gestures, making it suitable for mobile application development. However, it's worth noting that native mobile app development using languages like Java or Swift might offer better performance and access to platform-specific features.

  1. Are Python GUI frameworks suitable for developing complex and feature-rich applications, or are they only suitable for simple projects?

Python GUI frameworks are versatile and can be used for a wide range of applications, from simple to complex. While they excel in creating quick prototypes and user-friendly interfaces for smaller projects, they are equally capable of handling more substantial and feature-rich applications. Many Python GUI frameworks provide extensive libraries and tools, enabling developers to implement advanced features and complex functionality. Additionally, Python's rich ecosystem allows you to integrate with other libraries and technologies, making it a solid choice for ambitious software projects.

  1. Is Python a good option for GUI development?

Yes, Python is considered good for GUI development. It has a simple and easy-to-understand syntax, which makes it beginner-friendly and allows developers to quickly prototype and build GUI applications. Python's extensive library support, such as Tkinter, makes it convenient to create cross-platform GUIs. Additionally, Python's flexibility and availability on multiple platforms make it a popular choice for GUI development.